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2022 Yale Life Sciences Pitchfest Winners

1st Place

Anthony Koleske, Ensign Professor of Molecular Biophysics and Biochemistry and of Neuroscience; Deputy Dean for Research, (Basic Science)
Project: A screen for small molecule regulators of TRIO GEF1 activity 

2nd Place

Kevan Herold, C.N.H. Long Professor of Immunobiology and of Medicine (Endocrinology)
Project: Engineering beta cells for resistance to immune attack and reversal of diabetes

Farida Ahangari, Assistant Professor, Internal Medicine
Project: Targeting Profibrotic Macrophages Using Mir-33 Inhibitors, a Novel Therapeutic Approach for Pulmonary Fibrosis 

3rd Place

Anton Bennett, Dorys McConnell Duberg Professor of Pharmacology and of Comparative Medicine; Director, Yale Center for Molecular and Systems Metabolism
Project: Allagium Therapeutics, driving change to better health 

Ruslan Medzhitov, Sterling Professor of Immunobiology
Project: To identify a new class of therapeutics for inflammatory diseases

Ian Odell, Assistant Professor of Dermatology 
Project: Epiregulin Inhibition to Treat Scleroderma Skin and Lung Fibrosis

4th Place

Nicholas Economos, MD/PhD student
Project: Hybridex Biosciences, enabling the next generation of safe gene editing therapeutics.

Rohan Khera, Assistant Professor, Cardiovascular Medicine and Health Informatics 
Project: ENSIGHT-AI

One Year Free Bench Space c/o BioLabs New Haven

Choukri Ben Mamoun, Professor of Medicine and Microbial Pathogenesis
Project: Potentiators of AntiMicrobial Susceptibility

PRESENTERS

Therapeutics & Medical Devices

Farida Ahangari.jpg
Farida Ahangari, Assistant Professor, Internal Medicine
Project Summary

Targeting Profibrotic Macrophages Using Mir-33 Inhibitors, a Novel Therapeutic Approach for Pulmonary Fibrosis

Choukri Ben Mamoun headshot
Choukri Ben Mamoun, Professor of Medicine and Microbial Pathogenesis
Project Summary

Potentiators of AntiMicrobial Susceptibility

Anton Bennett headshot
Anton Bennett, Director, Yale Center for Molecular and Systems Metabolism
Project Summary

Allagium Therapeutics - Driving change to better health 

Marcus Bosenberg
Marcus Bosenberg, Anthony N. Brady Professor of Dermatology, Pathology, and Immunobiology
Project Summary

DNA methylation-based biomarkers for cancer therapy

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Christopher Bunick, Associate Professor of Dermatology
Project Summary

Reducing cancer metastasis by inhibiting vimentin filament assembly

Desir Head Shot
Gary Désir, Vice Provost for Faculty Development and Diversity; Chair, Department of Internal Medicine; and Paul B. Beeson Professor of Medicine
Project Summary

Modulation of the Renalase Pathway: First-in-class therapeutics for the treatment of acute pancreatitis and check-point resistant cancers

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Vicente Diaz, Chief of Ophthalmology
Project Summary

Extended Release Latanoprost Wafer for the Treatment of Glaucoma

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Tarek M. Fahmy, Associate Professor of Biomedical Engineering, Chemical & Environmental Engineeering and Immunobiology
Project Summary

ReImmune.  A dispsoable bed-side device for T cell Immunotherapy without Genetic Engineering

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Carlos Fernández-Hernando, Professor of Comparative Medicine and Pathology, Director Vascular Biology and Therapeutics Program
Project Summary

FABP5 as target for obesity-driven hepatocellular carcinoma

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Francine M. Foss, Professor of Medicine, Hematology and Cell Therapy
Project Summary

Targeted Therapy for T cell Lymphomas

Glazer
Peter Glazer, Robert E. Hunter Professor of Therapeutic Radiology and Professor of Genetics; Chair, Therapeutic Radiology
Project Summary

Hybridex Biosciences: Enabling the next generation of safe gene editing therapeutics. ***Nicholas Economos, MD/PhD Student, will be presenting. 

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Jaime Grutzendler, Professor of Neurology and Neuroscience Vice-Chair for Research, Neurology
Project Summary

Building the RABET™platform

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Kevan C. Herold, C.N.H. Long Professor of Immunobiology and of Medicine (Endocrinology)
Project Summary

Engineering beta cells for resistance to immune attack and reversal of diabetes

Anthony Koleske, PhD
Anthony Koleske, Ensign Professor of Molecular Biophysics and Biochemistry and of Neuroscience; Deputy Dean for Research, (Basic Science)
Project Summary

A screen for small molecule regulators of TRIO GEF1 activity

Ruslan Medzhitov.jpg
Ruslan Medzhitov, Sterling Professor of Immunobiology
Project Summary

To identify a new class of therapeutics for inflammatory diseases

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Markus Müschen, Chief, Cellular and Molecular Oncology
Project Summary

Targeting GSK3B in refractory B-cell malignancies

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Cassius Iyad Ochoa Chaar, Associate Professor in Vascular Surgery
Project Summary

Novel Device for Endovascular Retrieval of Inferior Vena Cava Filters

Ian Odell.jpg
Ian Odell, Assistant Professor of Dermatology
Project Summary

Epiregulin Inhibition to Treat Scleroderma Skin and Lung Fibrosis

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Thuy Tran, Assistant Professor of Medicine (Medical Oncology)
Project Summary

Targeting MIF - D-DT Signaling to Enhance Immunotherapy Responses in Cancer

Joseph Vinetz
Joseph M. Vinetz, Professor of Internal Medicine
Project Summary

Human Leptospirosis Vaccine Development Through Animal Health Product Development

Dianqing Wu
Dianqing Wu, Professor of Pharmacology
Project Summary

First-in-Class Humanized Anti-DKK2 for Colorectal Cancer

Anne Wyllie
Anne Wyllie, Research Scientist, Epidemiology
Project Summary

SalivaDirect: Championing equitable, accessible testing solutions for the pandemic and beyond. ***Yasmine Ali, Business Development Manager, will be presenting. 

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Jing Yan, Assistant Professor, MCDB
Project Summary

Biofilm-inspired bioadhesives

Digital Health

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Garrett Ash, Associate Research Scientist
Project Summary

Combination Therapy – Continuous Glucose Monitoring (CGM) Technology with Digital Fitness as a Therapy for Type 2 Diabetes

Lisa Fucito
Lisa Fucito, Associate Professor of Psychiatry
Project Summary

Health Data Integration

Rohan Khera
Rohan Khera, Assistant Professor, Cardiovascular Medicine and Health Informatics
Project Summary

ENSIGHT-AI

Mak Head Shot
Michael Mak, Assistant Professor, Biomedical Engineering
Project Summary

Biophysical Informatics Solutions

Darve
Darve Robinson, Clinical Fellow, Internal Medicine
Project Summary

ConsultUS: Your Digital Addiction Consultants

Curt Scharfe
Curt Scharfe, Associate Professor, Genetics
Project Summary

An Online Software Suite to Improve the Accuracy of Newborn Screening.

Minhee Sung
Minhee Sung, Instructor of Internal Medicine
Project Summary

EnligtheN: Wearable Overdose Detection

Siyuan (Steven) Wang
Siyuan (Steven) Wang, Assistant Professor of Genetics and Cell Biology
Project Summary

Judges

John Androsavich, PhD, Pfizer

Dr. John Androsavich
Global Head, RNA Emerging Science Lead, Pfizer

Alexandra Cantley, PhD, Polaris

Alexandra Cantley headshot
Polaris

Olga Danilchanka, PhD, MRLV

Olga
Principal at MRL Ventures Fund (MRLV)

Sean Evans, Johnson & Johnson Innovation

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Sean Evans, Associate, Venture Investments at Johnson & Johnson Innovation

Michael Gillespie, MD, RA Capital Management

Michael Gillespie
Life Sciences Investor, RA Capital Management

Jill Goldstein, Vida Ventures

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Associate, Vida Ventures

Alex Harding, MD, Remix Therapeutics

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Vice President of Business Development

Michelle Levine, Solasta Ventures

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Senior Associate, Solasta Ventures

Jonathan Mandelbaum, PhD, OrbiMed

Jonathan Mandelbaum
Vice President, OrbiMed

Jasmina Marjanovic, AbbVie Ventures

Jasmina Marjanovic
Director, AbbVie Ventures

Ronak Savla, PhD, Catalent Pharma Solutions

Ronak Savla
Director, Strategic Ventures, Catalent Pharma Solutions

Katie Spielberg, PhD, 5AM Ventures

Katie Spielberg
Associate, 5AM Ventures

Nilay Thakar, PhD, Arch Venture Partners

Nilay
Arch Venture Partners

Julie Wolf, PhD, 2048 Ventures

Julie Wolf
Principal, 2048 Ventures

Brian Yordy, Ph.D., F-Prime

Brian Yordy headshot
F-Prime
Thank you our sponsors
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