2022 PitchFest | Yale Ventures

2022 Yale Life Sciences Pitchfest Winners

1st Place

Anthony Koleske, Ensign Professor of Molecular Biophysics and Biochemistry and of Neuroscience; Deputy Dean for Research, (Basic Science)
Project: A screen for small molecule regulators of TRIO GEF1 activity

2nd Place

Kevan Herold, C.N.H. Long Professor of Immunobiology and of Medicine (Endocrinology)
Project: Engineering beta cells for resistance to immune attack and reversal of diabetes

Farida Ahangari, Assistant Professor, Internal Medicine
Project: Targeting Profibrotic Macrophages Using Mir-33 Inhibitors, a Novel Therapeutic Approach for Pulmonary Fibrosis

3rd Place

Anton Bennett, Dorys McConnell Duberg Professor of Pharmacology and of Comparative Medicine; Director, Yale Center for Molecular and Systems Metabolism
Project: Allagium Therapeutics, driving change to better health

Ruslan Medzhitov, Sterling Professor of Immunobiology
Project: To identify a new class of therapeutics for inflammatory diseases

Ian Odell, Assistant Professor of Dermatology
Project: Epiregulin Inhibition to Treat Scleroderma Skin and Lung Fibrosis

4th Place

Nicholas Economos, MD/PhD student
Project: Hybridex Biosciences, enabling the next generation of safe gene editing therapeutics.

Rohan Khera, Assistant Professor, Cardiovascular Medicine and Health Informatics
Project: ENSIGHT-AI

One Year Free Bench Space c/o BioLabs New Haven

Choukri Ben Mamoun, Professor of Medicine and Microbial Pathogenesis
Project: Potentiators of AntiMicrobial Susceptibility

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Therapeutics & Medical Devices

Farida Ahangari, Assistant Professor, Internal Medicine

Project Summary

Targeting Profibrotic Macrophages Using Mir-33 Inhibitors, a Novel Therapeutic Approach for Pulmonary Fibrosis

Choukri Ben Mamoun, Professor of Medicine and Microbial Pathogenesis

Project Summary

Potentiators of AntiMicrobial Susceptibility

Anton Bennett, Director, Yale Center for Molecular and Systems Metabolism

Project Summary

Allagium Therapeutics - Driving change to better health

Marcus Bosenberg, Anthony N. Brady Professor of Dermatology, Pathology, and Immunobiology

Project Summary

DNA methylation-based biomarkers for cancer therapy

Christopher Bunick, Associate Professor of Dermatology

Project Summary

Reducing cancer metastasis by inhibiting vimentin filament assembly

Gary Désir, Vice Provost for Faculty Development and Diversity; Chair, Department of Internal Medicine; and Paul B. Beeson Professor of Medicine

Project Summary

Modulation of the Renalase Pathway: First-in-class therapeutics for the treatment of acute pancreatitis and check-point resistant cancers

Vicente Diaz, Chief of Ophthalmology

Project Summary

Extended Release Latanoprost Wafer for the Treatment of Glaucoma

Tarek M. Fahmy, Associate Professor of Biomedical Engineering, Chemical & Environmental Engineeering and Immunobiology

Project Summary

ReImmune. A dispsoable bed-side device for T cell Immunotherapy without Genetic Engineering

Carlos Fernández-Hernando, Professor of Comparative Medicine and Pathology, Director Vascular Biology and Therapeutics Program

Project Summary

FABP5 as target for obesity-driven hepatocellular carcinoma

Francine M. Foss, Professor of Medicine, Hematology and Cell Therapy

Project Summary

Targeted Therapy for T cell Lymphomas

Peter Glazer, Robert E. Hunter Professor of Therapeutic Radiology and Professor of Genetics; Chair, Therapeutic Radiology

Project Summary

Hybridex Biosciences: Enabling the next generation of safe gene editing therapeutics. ***Nicholas Economos, MD/PhD Student, will be presenting.

Jaime Grutzendler, Professor of Neurology and Neuroscience Vice-Chair for Research, Neurology

Project Summary

Building the RABET™platform

Kevan C. Herold, C.N.H. Long Professor of Immunobiology and of Medicine (Endocrinology)

Project Summary

Engineering beta cells for resistance to immune attack and reversal of diabetes

Anthony Koleske, Ensign Professor of Molecular Biophysics and Biochemistry and of Neuroscience; Deputy Dean for Research, (Basic Science)

Project Summary

A screen for small molecule regulators of TRIO GEF1 activity

Ruslan Medzhitov, Sterling Professor of Immunobiology

Project Summary

To identify a new class of therapeutics for inflammatory diseases

Markus Müschen, Chief, Cellular and Molecular Oncology

Project Summary

Targeting GSK3B in refractory B-cell malignancies

Cassius Iyad Ochoa Chaar, Associate Professor in Vascular Surgery

Project Summary

Novel Device for Endovascular Retrieval of Inferior Vena Cava Filters

Ian Odell, Assistant Professor of Dermatology

Project Summary

Epiregulin Inhibition to Treat Scleroderma Skin and Lung Fibrosis

Thuy Tran, Assistant Professor of Medicine (Medical Oncology)

Project Summary

Targeting MIF - D-DT Signaling to Enhance Immunotherapy Responses in Cancer

Joseph M. Vinetz, Professor of Internal Medicine

Project Summary

Human Leptospirosis Vaccine Development Through Animal Health Product Development

Dianqing Wu, Professor of Pharmacology

Project Summary

First-in-Class Humanized Anti-DKK2 for Colorectal Cancer

Anne Wyllie, Research Scientist, Epidemiology

Project Summary

SalivaDirect: Championing equitable, accessible testing solutions for the pandemic and beyond. ***Yasmine Ali, Business Development Manager, will be presenting.