panluminate, Inc. is a Yale-spinout neurotech company building the infrastructure layer for whole-brain connectomics—the complete mapping of the brain's neural circuitry at nanoscale resolution.

Much like Illumina enabled the genomics revolution by providing the foundational tools to map the human genome, panluminate provides the full stack of chemistry, hardware, and software that makes connectomics possible at scale. Our integrated platform spans our patented pan-staining chemistry, the panoptix light sheet microscopy system, automated tissue expansion instrumentation, and AI-powered neuron tracing and analysis software.

The rich, nano-resolution datasets produced by our platform are purpose-built to train and ground foundation models for neuroscience and drug development, establishing panluminate as critical infrastructure for the next generation of biological AI. Beyond the brain, our technology is applicable across any organic tissue—including kidney, lung, and heart—enabling broad applications in rare disease research and pharmaceutical development.

Founded at Yale University and headquartered in New Haven, CT, panluminate is building the data foundation that will define the future of brain science and AI-driven medicine.