Our platform revolutionizes heart failure care by transforming complex genetic data into clear, actionable insights. Unlike existing polygenic risk tools, it not only quantifies risk but explains why it exists, where it originates, and how it can be managed. Using AI and multi-omics integration, it maps variant-driven pathways—such as inflammation or fibrosis—to targeted therapeutic options. Clinicians gain mechanistic visibility into each patient’s biology, enabling precision drug selection and early intervention. This first-in-class, explainable genomics platform bridges discovery and care, unlocking scalable opportunities across cardiovascular, metabolic, and aging-related diseases.