Duotap is a novel active derivative of tapinarof

• Stilbenes are readily derivatized for optimization to purpose (A) – Duotap is a tractable scaffold for further derivatization (B).
• Duotap is active form of tapinarof as an antibiotic
  • Duotap is the active metabolite dimer of tapinarof against MRSA (C) and VRE.
  • Duotap does not give rise to resistance (D).
• Intellectual Property
  • Compositions and uses.
    • Antibiotics