Human Matrix-Polymer Scaffold
PEGylated Amnion scaffold for use in wound management
A wound repair hydrogel that combines the benefits of amnion ‘scarless healing’ with a hydrogel scaffold that conforms to the wound. It can be applied as a gel and cured in white light, or as a prefab dressing providing a much longer shelf-life than amnion sheets.
Advantages compared with amnion sheet:
- Significantly less wound contraction.
- 2x faster surface closure.
- Lower infection risk (animal data).
- 8 times less amnion used.
- Utilizes FDA approved materials.
- Conforms to the wound and provides greater shear strength in healing.
Applications:
- Diabetic foot ulcers
- Corneal repair
- Burn wounds
- The mechanical properties of the hydrogel (mechanical stiffness of the scaffold, individual pore size and porosity) can be tuned through a crystal templating method developed at Yale.