PEGylated Amnion scaffold for use in wound management

A wound repair hydrogel that combines the benefits of amnion ‘scarless healing’ with a hydrogel scaffold that conforms to the wound. It can be applied as a gel and cured in white light, or as a prefab dressing providing a much longer shelf-life than amnion sheets.

Advantages compared with amnion sheet:

• Significantly less wound contraction.
• 2x faster surface closure.
• Lower infection risk (animal data).
• 8 times less amnion used.
• Utilizes FDA approved materials.
• Conforms to the wound and provides greater shear strength in healing.

Applications:

• Diabetic foot ulcers
• Corneal repair
• Burn wounds
• The mechanical properties of the hydrogel (mechanical stiffness of the scaffold, individual pore size and porosity) can be tuned through a crystal templating method developed at Yale.