Whole Cell Vaccine/Adjuvant Platform

Effective vaccines against many bacteria require T cell immunity, but few vaccines elicit such responses
OCR6913 is chemical technique for attaching a T cell-stimulating adjuvant (CPX2) directly to bacteria
This adjuvant potently activates T cell- promoting signals through TLR7
Demonstrated protective effect of the vaccine in vivo in S. aureus bacteremia model
This chemistry allows synthesis of whole cell vaccines against any culturable bacteria or fungus