Novel Vaccine for Leptospirosis

Leptospira is a major veterinary pathogen and can cause a life-threatening disease in humans.
Current vaccines provide limited protective value.
Yale researchers have generated a live, attenuated strain of Leptospira that provides protective immunity.
Vaccination with this strain protects against a lethal challenge with various Leptospira species.
OCR6320 is a safe and efficacious novel vaccine candidate for the treatment of Leptospira infections.
Publication: Mol Microbiol. 2016 Aug;101(3):457-70
Partnered for vet use; Human use still available.
Patent Application: PCT/US15/19865
Lead Innovator: Albert Ko, M.D.