Dr. Carrie L. Lucas received her PhD from Harvard Medical School and her postdoctoral training from the National Institutes of Health, NIAID. Her laboratory discovers single-gene defects underlying severe immune disorders in humans and investigates mechanisms using patient cells and genetically engineered mouse models. A major focus of her work has been on phosphoinositide 3-kinase (PI3K) signaling and mechanisms of disease in immunodeficient patients with mutations in PI3K subunits.