The Mak Research Lab is focused on multiscale mechanobiology in cancer and development. We develop interdisciplinary approaches, integrating microfluidics, computational modeling, and novel experimental systems, to decipher the principles driving emergent mechanobiological phenomena from the molecular to multicellular scales, including structure formation and functionality of cytoskeletal networks, invasive behavior of tumor cells, and collective dynamics of tumors, organoids, and tissues. We aim to bridge the gap between molecular signatures and mechanical phenotypes, especially in cancer metastasis and tissue morphogenesis.