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Methods of Increasing Pluripotency of Stem Cells

Methods of Increasing Pluripotency of Stem Cells

  • Yale scientists have developed novel methods of increasing pluripotency of stem cells. The methods include contacting stem cells with Rhoassociated kinase inhibitor and Arp2/3 complex inhibitor, which together increase the pluripotency of stem cells in a surprising and synergistic manner.
  • These methods can be useful for treatment of cancer, fibrosis, and/or inflammation.
  • Reference: Nat Commun. 2019 Apr 12;10(1):1695
  • Intellectual property – patent application pending