Yale Technology Spotlight: Latent Bio
Latent Bio resides at the intersection of geometric deep learning, chemistry, biology, and clinical data—reimagining how drugs are discovered and optimizing translation to and through the clinic.
With scientific roots in Yale's Krishnaswamy Lab, Latent Bio is implementing practical, business-focused, applications of GDL for drug discovery, biomarker discovery, and characterization of clinical populations to optimize assets for clinical development and partnerships.
The company has engaged with Krishnaswamy Lab’s deep expertise in geometric and manifold-based machine learning to build a platform that reads the true underlying shape and structure of biological and chemical data. This enables Latent Bio and its partners to navigate toward promising drug discoveries with far greater precision than traditional methods allow. Where conventional drug development relies on slow, iterative cycles of molecular tweaking and screening, Latent Bio's technology compresses that process, helping itself and R&D partners identify the right molecules and biomarkers faster and with greater confidence. For pharmaceutical partners and biotech researchers working across many indications, this is a platform built to make drug discovery and development smarter from the start.
FOUNDED
2025
New Haven, CT
FOUNDERS
Smita Krishnaswamy, Professor of Genetics and of Computer Science, Co-founder and Chief Scientific Officer; David Kolb, Co-founder and CEO
STAGE
Seeking $5M Seed Funding for internal pipeline development
CORE TECHNOLOGY
Geometric Deep Learning (GDL) for Accelerated Drug Discovery & Development
About Latent Bio
Latent Bio decodes the geometry of biological, chemical, and clinical data to create solutions for patients and value for partners. We are building on the concepts and tools pioneered by the Krishnaswamy Lab and are grateful for our relationship with Yale and for the on-going support of Yale Ventures.
— David Lewin, PhD; President, Latent Bio