Cell Penetrating Anti-Guanosine Antibody Therapeutic for Cancer with Ras Mutations
Cell Penetrating Anti-Guanosine Antibody Therapeutic for Cancer with Ras Mutations
Background: An antibody has been identified in a mouse model of lupus with anti-guanosine activity and is capable of cellular penetration. This antibody has potential as a therapeutic agent for tumors driven by K-Ras. It can also be conjugated to a nanoparticle to deliver other therapeutics.
Indications: Malignancies associated with mutant K-Ras
Innovation: Cell penetrating antibody therapeutic, active against K-Ras
