Lars Onsager was a Norwegian-born American physical chemist and  theoretical physicist. He joined Yale's faculty in 1933 and held the Gibbs Professorship of Theoretical Chemistry at Yale University. He was awarded the Nobel Prize in Chemistry in 1968.

Dr. Blackburn was a postdoctoral research at Yale from 1975 to 1977.  In 1984, Blackburn co-discovered telomerase, the enzyme that replenishes the telomere, with Carol W. Greider. She won the 2009 Nobel Prize in Physiology or Medicine for this work. 

Dr. Doudna joined Yale's Department of Molecular Biophysics and Biochemistry as an assistant professor in 1994, and served as the Henry Ford II Professor of Molecular Biophysics and Biochemistry at Yale from 2000 to 2002. Her pioneering work in CRISPR gene editing was awarded the 2020 Nobel Prize in Chemistry along with Emmanuelle Charpentier.

Sidney Altman is the Sterling Professor of Molecular, Cellular, and Developmental Biology and Chemistry at Yale University. He joined Yale as an assistant professor in 1971. In 1989 he shared the Nobel Prize in Chemistry with Thomas R. Cech for their work on the catalytic properties of RNA.

James Edward Rothman (BA '71) is the Fergus F. Wallace Professor of Biomedical Sciences at Yale University, the Chairman of the Department of Cell Biology at Yale School of Medicine, and the Director of the Nanobiology Institute at the Yale West Campus.^[4] Rothman was awarded the 2013 Nobel Prize in Physiology or Medicine, for his work on vesicle trafficking.

Dr. Ramakrishnan began work on ribosomes as a postdoctoral fellow at Yale University. He shared the 2009 Nobel Prize in Chemistry with Thomas A. Steitz and Ada Yonath, "for studies of the structure and function of the ribosome." Dr. Ramakrishnan served as President of the Royal Society from 2015-2020.

Dr. Steitz was an American biochemist, a Sterling Professor of Molecular Biophysics and Biochemistry at Yale University, and investigator at the Howard Hughes Medical Institute, best known for his pioneering work on the ribosome. He joined the Yale faculty in 1970.

Steitz was awarded the 2009 Nobel Prize in Chemistry along with Venkatraman Ramakrishnan and Ada Yonath "for studies of the structure and function of the ribosome".

A pioneer of brain surgery, Harvey Cushing founded Neurosurgery as an independent specialty, established the concept of the physician scientist, founded Endocrinology through studies of hormones and pituitary tumors, and brought blood pressure monitoring and the use of x-ray imaging into the operating room. He graduated with an A.B. degree in 1891 from Yale University and returned in 1933 as the Sterling Professor of Medicine. Opened in 2010, the Cushing Center houses The Cushing Tumor Registry, an archival collection of over 2,200 case studies which includes human whole brain and tumor specimens, microscopic slides, note books, journal excerpts, and over 15,000 photographic negatives dating from the late 1800’s to 1936.

Dr. Schlessinger joined Yale as the William H. Prusoff Professor and Chairman of the Department of Pharmacology at the Yale School of Medicine in 2001. Schlessinger's work has led to an understanding of the mechanism of transmembrane signaling by receptor tyrosine kinases^[2] and how the resulting signals control cell growth and differentiation. He has founded 3 biotechnology companies, and currently has 4 drugs approved by the FDA.