Anative of Guangzhou, China, Junjie Guo received his B.A. in Biology from Peking University (Beijing). He completed his Ph.D. thesis in the Solomon H. Snyder Department of Neuroscience at Johns Hopkins University School of Medicine, working with Hongjun Song on neuronal DNA methylation in the adult brain. During his postdoctoral training in David Bartel's laboratory at the Whitehead Institute/MIT, Guo developed a series of high-throughput computational and experimental methods to investigate circular RNAs and intracellular RNA folding. He joined the Department of Neuroscience at Yale School of Medicine in Fall 2017.

The Guo lab is broadly interested in questions at the intersection of RNA biology and neuroscience, with an emphasis on developing and applying new tools to investigate RNA-based gene regulatory mechanisms in the nervous system. Research in the lab aims to understand how these mechanisms may be specialized in the nervous system as well as their roles in neurological diseases.